2005-2013 Mercedes-Benz S-Class (W221) and CL-Class (C216)

01.09.2017 (US:09.01.17), Category: Mercedes / S-Class

Fuse and relay box in rear

2005-2013 Mercedes-Benz S-Class (W221 and C216) Fuses Box Location
Opening: Swing down center armrest.
Open cover behind center armrest.
Pull cover 1 forward in direction of arrow.
Closing: Press cover 1 backward and engage
2005-2013 Mercedes-Benz S-Class (W221 and C216) Fuses Box Layout


Fuses Specifications
No. A Description
115 50 Heated rear window
116 10 M157, M275, M278: Charge air cooler circulation pump
M156: Engine coolant circulation pump
S 400 Hybrid: Power electronics circulation pump 2
117 15 Rear cigar lighter
118 30 M272, M273, OM642: Fuel pump (→2008)
W221 with OM629, OM642: Fuel pump (2009→)
15 S 400 Hybrid: Power electronics circulation pump 1
OM642.8 and OM651 (01.06.2011→): Refrigerant compressor with magnetic
119 7.5 Front central operating unit
120 - -
121 10 Audio tuner control unit
122 7.5 COMAND controller unit
123 40 W221: Right front reversible emergency tensioning retractor
124 40 W221: Left front reversible emergency tensioning retractor
125 5 →31.05.2009: Voice control system (VCS) control unit
126 25 Overhead control panel control unit
127 30 Lumbar pump (2009→)
Multicontour seat pneumatic pump (Left/right front multicontour seats)
Pneumatic pump for dynamic seat control (Left and right dynamic multicontour seat)
128 25 M275 (→2008): Fuel pump control unit
M156, M157, M272, M273, M275, M276, M278, OM642 (2009→): Fuel pump control unit
129 25 →2008: Overhead control panel control unit (Power glass tilting/sliding roof)
2009→: UPCI (Universal Portable Cell Phone Interface) control unit
130 30 Electric parking brake controller unit
131 7.5 Rear window antenna amplifier module
133 15 Trailer recognition control unit
Reversing camera (01.09.2010→)
134 15 Luggage compartment socket
135 7.5 Park Assist (→2008):
   Radar sensors control unit (SGR)
   Front short range radar sensor unit
   Rear short range radar sensor unit
DISTRONIC PLUS →31.08.2010 or Blind Spot Assist or Adaptive cruise control Plus Light: Radar sensors control unit (SGR) (2009→)
PARKTRONIC or Exclusive parking assist: PTS control unit
136 7.5 W221 with OM642.8: AdBlue® control unit
137 7.5 Reversing camera (01.09.2010→)
138 5 Navigation processor (2009-31.08.2010)
Emergency call system control unit (2009→)
Japan: TV/tuner connector (2009→)
139 15 Rear backrest refrigerator box
140 15 Rear cigar lighter with ashtray illumination connector
115 V socket (2009→)
141 5 Reversing camera control unit
142 7.5 Parktronic system (PTS) control unit
Distronic Plus: Radar sensors control unit (SGR)
01.09.2010→ for DISTRONIC PLUS and Active Blind Spot Assist or Active Lane Keeping Assist:
   Video and radar sensor system control unit
143 25 Rear seats control unit
144 25 Rear seats control unit
145 20 Trailer recognition control unit (→2008)
Trailer hitch socket (13-pin) (2009→)
146 25 Trailer recognition control unit
147 30 →2008: TLC [HDS] control unit (Remote trunk closing)
148 7.5 →2008: Universal Portable CTEL Interface (UPCI [UHI]) control unit
25 2009→: Panoramic sliding sunroof circuit 30 connector sleeve
149 5 →2008: Voice control system (VCS [SBS]) control unit
25 2009→: Panoramic sliding sunroof control module
150 7.5 TV combination tuner (analog/digital)
Japan: TV/tuner connector (2009→)
151 25 W221; →2008: Electric parking brake controller unit
20 W221; 2009→: Trailer recognition control unit
152 7.5 W221: Rear window antenna amplifier module
25 115 V socket: DC/AC converter control unit
Relay
M Terminal 15
N Terminal 15R
O Power outlet
P Heated rear window
Q M156, M157, M275, M278, OM629: Circulation pump
S 400 Hybrid: W221.095/195: Power electronics circulation pump 2
R Cigar lighter
S Fuel pump
OM642.8 and engine OM651 (01.06.2011→): Connected through the fuel pump: Refrigerant compressor magnetic clutch
S 400 Hybrid: Power electronics circulation pump relay 1

Gasoline:

  • 3.0L - M272 (S300)
  • 3.5L - M272 (S350, S350 BlueEFFICIENCY, S400 Hybrid)
  • 4.7L - M273 (S450)
  • 5.5L - M273 (S500 / S550) 
  • 5.5L - M157 (S63 AMG)
  • 5.5L - M275 (S600)
  • 6.0L - M275 (S65 AMG)
  • 6.2L - M156 (S63 AMG) 

Diesel:

  • 2.2L - OM651 (S250 CDI BlueEFFICIENCY)
  • 3.0L - OM642 (S320 CDI, S320 CDI BlueEFFICIENCY, S350 CDI BlueEFFICIENCY, S350 BlueTEC)
  • 4.0L - OM629 (S420 CDI, S450 CDI)

CL-Class (C216)

  • 4.7L - M276 (CL 500)
  • 5.5L - M273 (CL 500)
  • 5.5L - M157 (CL 63 AMG)
  • 5.5L - M275 (CL 600)
  • 6.0L - M275 (CL 65 AMG)
  • 6.2L - M156 (CL 63 AMG) 

Fuse box in the engine compartment

2005-2013 Mercedes-Benz S-Class (W221 and C216) Fuse Box Chart


Fuses Specifications
No. A Description
20 10 OM629, OM642, OM651:
   CDI control unit
M156, M157, M272, M273, M275, M276, M278:
   ME-SFI [ME] control unit
21 20 M156, M157, M272, M273, M275, M276, M278:
   Terminal 87 M1 i connector sleeve
W221 with OM629 and engine OM642:
   CDI control unit
   Fuel pump relay
W221 with OM651:
   Quantity control valve
22 15 M156, M157, M272, M273, M276, M278:
   Terminal 87 connector sleeve
23 20 →2008:
   Terminal 87 connector sleeve
   M275 (C216):
      Terminal 87 M1 i connector sleeve
   M273 (C216):
      Terminal 87 M2e connector sleeve
   M272, M273 (W221):
      Terminal 87M2i connector sleeve
   OM642:
      Terminal 87 connector sleeve
2009→:
   M156, M157, M272, M273, M275, M276, M278:
      Terminal 87 connector sleeve
   W221 with OM629 and engine OM642:
      Terminal 87 connector sleeve
   M156, M157, M272, M273, M276, M278:
      Terminal 87M2e connector sleeve
   M275:
      Terminal 87 M2i connector sleeve
   W221 with OM629 and engine OM642:
      Terminal 87 connector sleeve
   W221 with OM651:
      Rear SAM control unit with fuse and relay module
24 25 M157, M272, M273, M276, M278:
   Terminal 87M1e connector sleeve
OM642:
   CDI control unit
25 7.5 Instrument cluster
26 10 Left front lamp unit
27 10 Right front lamp unit
28 7.5 M275:
   EGS control unit
except M275:
   Fully integrated transmission control (VGS) control unit
29 5 Rear SAM control unit with fuse and relay module
30 7.5 OM629, OM642, OM651:
   CDI control unit
M156, M157, M272, M273, M275, M276, M278:
   ME-SFI [ME] control unit
   Fuel pump control unit
31 5 S 400 Hybrid: Electric refrigerant compressor
32 15 ECO start/stop function: 
   Transmission oil auxiliary pump control unit
S 400 Hybrid:
   Transmission oil auxiliary pump control unit
33 5 01.09.2010→ (except S 400 Hybrid):
   ESP control unit
S 400 Hybrid:
   Battery management system control unit
   DC/DC converter control unit
   Power electronics control unit
34 5 S 400 Hybrid: Regenerative braking system control unit
35 5 Electric parking brake controller unit
36 10 Data link connector (Pin 16)
37 7.5 For EIS control unit
38 7.5 Central gateway control unit
39 7.5 Instrument cluster
40 7.5 Upper control panel control unit
41 30 Slave wiper motor
42 30 Master wiper motor
43 15 Front cigar lighter with ashtray illumination
44 - -
45 5 S 400 Hybrid: Power electronics circulation pump 1
46 15 W221 with Active Body Control (ABC), C216: ABC control unit
W221 without Active Body Contro (ABC): AIRmatic with ADS control unit
47 15 Front SAM control unit with fuse and relay module
Steering column up/down motor
48 15 →2008: Front SAM control unit with fuse and relay module
2009→: Steering column in/out motor
49 10 Steering column module
50 15 AAC [KLA] control unit
51 7.5 →2008: COMAND display
5 2009→:
   COMAND display
   SPLITVIEW display
52A 15 W221: 
   Left fanfare horn
   Right fanfare horn
52B 15 W221, C216: 
   Left fanfare horn
   Right fanfare horn
53 - -
54 40 AC air recirculation unit
55 60 Gasoline: Electric air pump
56 40 W221 without Active Body Contro (ABC): AIRmatic compressor unit
57 40 →2008: Wiper park position heater
30 2009→: Wiper park position heater
60 5 2009→: Electrohydraulic power steering
61 7.5 C216; W221 (2009→): Restraint systems control unit
10 W221 (→2008): Restraint systems control unit
62 5 Night View Assist control unit
63 15 W221 with OM629 OM642 (01.09.2008→): Fuel filter condensation sensor with heating element
64 7.5 W221 (01.09.2006→):
   Driver NECK-PRO head restraint solenoid
   Front passenger NECK-PRO head restraint solenoid
10 W221 (2009→):
   Driver NECK-PRO head restraint solenoid
   Front passenger NECK-PRO head restraint solenoid
65 15 01.06.2009→: 12 Volt connector in glove box
66 7.5 DTR controller unit (Distronic or Distronic Plus)
Relay
A Air pump
B Air suspension compressor
C Terminal 87 (engine)
D Terminal 15
E Terminal 87 (chassis)
F Fanfare horn
G Terminal 15R
H Circuit 50, (starter)
J Circuit 15, (starter)
K Wiper park heater

Left instrument panel fuse box

2005-2013 Mercedes-Benz S-Class (W221 and C216) Fuse Panel Location
2005-2013 Mercedes-Benz S-Class (W221 and C216) Fuse Panel Diagram


Fuses Specifications
No. A Description
92 40 Left front seat control unit
93 7.5 Restraint systems control unit
USA: Weight Sensing System (WSS) control unit
94 5 2009→: Multifunction camera
95 - -
96 5 Tire pressure monitor [RDK] control unit
97 7.5 W221: Audio/video controller control unit (rear entertainment system)
98 7.5 Rear entertainment system: DVD player (2009→)
99 7.5 2009→:
   COMAND display
   SPLITVIEW display
100 5 2009→: Media interface control unit
101 10 Rear entertainment system:
   Left rear display
   Right rear display
102 40 Right front seat control unit
103 7.5 ESP control unit
104 40 Audio tuner control unit
105 - -
106 1 Japan: Electronic toll collection (ETC) control unit
South Korea (01.09.2010→): TV/tuner connector
Valid for navigation (2009→): Navigation processor
107 5 SDAR control unit (SIRIUS satellite radio) (W221 2009→)
Digital radio: Digital Audio Broadcasting control unit
HD radio: High definition tuner control unit
108 5 W221: Rear air conditioning control unit
109 15 W221: Rear blower intermediate connector
110 7.5 W221:
   Left rear multicontour backrest control unit
   Right rear multicontour backrest control unit
111 5 Rear multicontour seat or rear entertainment system (W221): RCP [HBF] control unit
112 5 W221 (→2008):
   Left front door control unit
   Right front door control unit
S 400 Hybrid: Front SAM control unit with fuse and relay module
113 5 S 400 Hybrid: DC/DC converter control unit

Right instrument panel fuse box

2005-2013 Mercedes-Benz S-Class (W221 and C216) Fuses Block Location
2005-2013 Mercedes-Benz S-Class (W221 and C216) Fuse Block Diagram


Fuses Specifications
No. A Description
70 40 C216: Right door control unit
W221: Right front door control unit
71 15 Keyless Go control unit
72 7.5 S 400 Hybrid: Pyrotechnical separator
73 5 Japan: COMAND controller unit
TELE AID emergency call system (2009→): Emergency call system control unit
74 30 TLC [HDS] control unit (Remote trunk closing)
75 10 S 400 Hybrid:
   Battery management system control unit
   Power electronics control unit
76 15 S 400 Hybrid: Vacuum pump relay (+)
- W221 with OM642.8: AdBlue® relay supply
77 50 Advanced sound system: Sound amplifier (2009→)
78 25 S 65 AMG with M275:
   Additional fan relay (2009→)
W221 with OM642.8:
   AdBlue® relay supply (2009→)
15 S 400 Hybrid, CL 63 AMG with M157, M278:
   Charge air cooler circulation pump (2009→)
79 7.5 Alarm signal horn with additional battery
80 40 C216: Left door control unit
W221: Left front door control unit
81 30 C216: Rear control unit
40 W221: Left rear door control unit
82 30 C216: Rear control unit
40 W221: Left rear door control unit
83 30 Intelligent servo module for DIRECT SELECT
84 20 Advanced sound system: Digital sound processor (2009→)
85 10 AMG: Illuminated door sill moldings (2009→)
86 - -
87 - -
88 - -
89 - -
90 20 Stationary heater:
   STH heater unit (C216)
   STH or HB heater unit (W221)
91 5 Stationary heater:
   STH radio remote control receiver
S 400 Hybrid:
   Front SAM control unit with fuse and relay module

Interior prefuse box (→2008)

2005-2008 Mercedes-Benz S-Class (W221 and C216) High Fuse Block
Fuses Specifications
No. A Description
1 400 Starter
2 150
200
except OM642:
   Alternator
OM642:
   Alternator
3 150 -
4 150 AAC with integrated control additional fan motor
5 200 OM642: PTC heater booster
6 200 Front SAM control unit with fuse and relay module
7 40 ESP control unit
8 25 ESP control unit
9 20 Front SAM control unit with fuse and relay module
10 7.5 Vehicle power supply control unit


Interior prefuse box (2009→)

2009-2013 Mercedes-Benz S-Class (W221 and C216) High Fuse Block
Fuses Specifications
No. A Description
3 150 Rear SAM control unit with fuse and relay module
4 150 ECO start/stop function:
   ECO start/stop function relay
S 400 Hybrid:
   DC/DC converter control unit
Heated windshield:
   Heated windshield control unit
5 125 W221 (Electrical preinstallation for rental vehicle):Special vehicle multifunction control unit (SVMCU [MSS])
40 S 400 Hybrid: Vacuum pump
6 80 Right dashboard fuse box
7 150 W221 with OM629, OM642, OM651:
   PTC heater booster
W221 (Electrical preinstallation for rental vehicle):
   Special vehicle multifunction control unit (SVMCU [MSS])
8 80 Front SAM control unit with fuse and relay module
9 80 Left dashboard fuse box
10 150 Rear SAM control unit with fuse and relay module

Engine compartment prefuse box (→2008)

2005-2008 Mercedes-Benz S-Class (W221 and C216) High Fuse Block
Fuses Specifications
No. A Description
1 ' Front prefuse box
(via on-board electrical network line pyrofuse
2 125 Heated windshield control unit
3 80 Right instrument panel fuse box
4 200 Rear SAM control unit with fuse and relay module
5 100 Special vehicle multifunction control unit (SVMCU [MSS])
6 150 Rear SAM control unit with fuse and relay module
7 100 Front SAM control unit with fuse and relay module
8 80 Left instrument panel fuse box
9 5 Front SAM control unit with fuse and relay module
10 5 C216: Emergency call system control unit

Engine compartment prefuse box (2009→)

2009-2013 Mercedes-Benz S-Class (W221 and C216) High Fuse Box
Fuses Specifications
No. A Description
2 400 Alternator
3 150 Electrohydraulic power steering
W221 with OM629, OM642:
   Glow time output stage
4 - Interior prefuse box ( unfused)
5 100 AAC with integrated control additional fan motor
6 150 Front SAM control unit with fuse and relay module
7 40 ESP control unit
S 400 Hybrid: Regenerative braking system control unit
8 25 ESP control unit
S 400 Hybrid: Regenerative braking system control unit
9 25 Front SAM control unit with fuse and relay module
10 - -

AdBlue fuse block

2009-2013 Mercedes-Benz S-Class (W221 and C216) AdBlue Fuse Box

2009-2013 Mercedes-Benz S-Class (W221 and C216) AdBlue Fuse Block Diagram
Fuses Specifications
No. A Description
A 7.5 AdBlue® control unit
B 20 Heater circuit 1
C 20 Heater circuit 2
D - -

Location and description of fuses and relay Mercedes-Benz W221 and C216,2.2L (S250 CDI), 3.0L (S300, S320 CDI, S350 CDI), 3.5L (S350, S400 Hybrid), 4.0L (S420 CDI, S450 CDI), 4.7L (S450, CL 500), 5.5L (S500 / S550, CL 500, S600, CL 600, S63 AMG, CL 63 AMG), 6.0L (S65 AMG, CL 65 AMG), 6.2L (S63 AMG, CL 63 AMG)  (2005, 2006, 2007, 2008, 2009, 2010, 2011, 2012, 2013)